Hasil FP2 MotoGP Le Mans 2016, pada latihan bebas kedua ini Jorge Lorenzo berhasil menjadi pembalap tercepat dengan catatan waktu 1 menit 32,830 detik, Dani Pedrosa yang berhasil mencatatkan waktu tercepat hanya bisa menempati posisi ke delapan pada latihan bebas 2 MotoGP Le Mans 2016 ini.
Diposisi kedua ada pembalap Ducati Andrea Iannone, dan tempat ketiga dihuni pembalap tim Repsol Honda Marc Marquez, pembalap muda Spanyol ini konsisten di posisi 3 besar pada FP1 dan FP2 MotoGP Le Mans 2016.
Valentino Rossi pada FP2 MotoGP Le Mans ini melorot ke posisi ke 10 tepat diatas hector Barbera yang menempati posisi ke 11. berikut hasil lengkap FP2 MotoGP Le Mans 2016 :
| Pos. | Num. | Rider | Nation | Team | Bike | Km/h | Time | Gap 1st/Prev. |
|---|---|---|---|---|---|---|---|---|
| 1 | 99 | Jorge LORENZO | SPA | Movistar Yamaha MotoGP | Yamaha | 311.5 | 1'32.830 | |
| 2 | 29 | Andrea IANNONE | ITA | Ducati Team | Ducati | 314.4 | 1'33.169 | 0.339 / 0.339 |
| 3 | 93 | Marc MARQUEZ | SPA | Repsol Honda Team | Honda | 307.4 | 1'33.313 | 0.483 / 0.144 |
| 4 | 44 | Pol ESPARGARO | SPA | Monster Yamaha Tech 3 | Yamaha | 309.1 | 1'33.406 | 0.576 / 0.093 |
| 5 | 4 | Andrea DOVIZIOSO | ITA | Ducati Team | Ducati | 315.7 | 1'33.574 | 0.744 / 0.168 |
| 6 | 41 | Aleix ESPARGARO | SPA | Team SUZUKI ECSTAR | Suzuki | 304.0 | 1'33.595 | 0.765 / 0.021 |
| 7 | 25 | Maverick VIÑALES | SPA | Team SUZUKI ECSTAR | Suzuki | 307.1 | 1'33.613 | 0.783 / 0.018 |
| 8 | 26 | Dani PEDROSA | SPA | Repsol Honda Team | Honda | 308.8 | 1'33.748 | 0.918 / 0.135 |
| 9 | 8 | Hector BARBERA | SPA | Avintia Racing | Ducati | 311.0 | 1'33.951 | 1.121 / 0.203 |
| 10 | 46 | Valentino ROSSI | ITA | Movistar Yamaha MotoGP | Yamaha | 305.9 | 1'33.974 | 1.144 / 0.023 |
| 11 | 9 | Danilo PETRUCCI | ITA | OCTO Pramac Yakhnich | Ducati | 309.8 | 1'34.050 | 1.220 / 0.076 |
| 12 | 35 | Cal CRUTCHLOW | GBR | LCR Honda | Honda | 309.1 | 1'34.053 | 1.223 / 0.003 |
| 13 | 45 | Scott REDDING | GBR | OCTO Pramac Yakhnich | Ducati | 310.3 | 1'34.083 | 1.253 / 0.030 |
| 14 | 38 | Bradley SMITH | GBR | Monster Yamaha Tech 3 | Yamaha | 308.4 | 1'34.306 | 1.476 / 0.223 |
| 15 | 76 | Loris BAZ | FRA | Avintia Racing | Ducati | 302.3 | 1'34.364 | 1.534 / 0.058 |
| 16 | 50 | Eugene LAVERTY | IRL | Aspar Team MotoGP | Ducati | 308.7 | 1'34.425 | 1.595 / 0.061 |
| 17 | 68 | Yonny HERNANDEZ | COL | Aspar Team MotoGP | Ducati | 307.0 | 1'34.531 | 1.701 / 0.106 |
| 18 | 43 | Jack MILLER | AUS | Estrella Galicia 0,0 Marc VDS | Honda | 304.7 | 1'34.656 | 1.826 / 0.125 |
| 19 | 6 | Stefan BRADL | GER | Aprilia Racing Team Gresini | Aprilia | 300.2 | 1'34.742 | 1.912 / 0.086 |
| 20 | 53 | Tito RABAT | SPA | Estrella Galicia 0,0 Marc VDS | Honda | 299.8 | 1'34.789 | 1.959 / 0.047 |
| 21 | 19 | Alvaro BAUTISTA | SPA | Aprilia Racing Team Gresini | Aprilia | 305.5 | 1'35.089 | 2.259 / 0.300 |
